We recently completed Stage One, of a multicentre study based on a large collaborative effort, aimed at understanding the safety and efficacy of probiotic therapy, on days alive and out of hospital, in adult intensive care unit (ICU) patients.

The Restoration Of gut microflora in Critical Illness Trial (ROCIT) was designed to assess whether, in adult patients admitted to ICUs, early and sustained daily administration of a probiotic therapy based on Lactobacillus plantarum (299v) was associated with an increase in days alive and out of hospital to day 60 (DAOH60), compared with placebo.

So…are probiotics safe and effective in ICU patients? To learn about the preliminary results of the ROCIT…

…read our open access paper here!

(Photo credit: Wikimedia Commons)